|Full Name||ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)|
|Product Description||Rabbit Polyclonal antibody to UBE2E3 (ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast))|
|Background||The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse and rat counterparts, which indicates that this enzyme is highly conserved in eukaryotes. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]|
|Synonyms||UBCH9 antibody, UbcM2 antibody, UBE2E3 antibody, ubiquitin-conjugating enzyme E2E 3 (homologous to yeast UBC4/5) antibody, ubiquitin-protein ligase E3 antibody, ubiquitin carrier protein E3 antibody, ubiquitin-conjugating enzyme E2 E3 antibody, ubiquitin-conjugating enzyme E2-23 kDa antibody, "ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast) antibody"|
|Cellular Localization||Nucleus , Cytoplasm |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human UBE2E3. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Rat, Zebrafish, Xenopus laevis, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Human (100%), Rat (100%), Zebrafish (95%), Xenopus laevis (98%), Chicken (99%), Rhesus Monkey (99%), Bovine (100%)|