|Full Name||ubiquitin protein ligase E3C|
|Product Description||Rabbit Polyclonal antibody to UBE3C (ubiquitin protein ligase E3C)|
|Background||E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Can assemble unanchored poly-ubiquitin chains in either 'Lys-29'- or 'Lys-48'-linked polyubiquitin chains. Has preference for 'Lys-48' linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo. |
|Synonyms||KIAA0010 antibody, KIAA10 antibody, UBE3C antibody, ubiquitin-protein isopeptide ligase (E3) antibody, ubiquitin-protein ligase E3C antibody, ubiquitin protein ligase E3C antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human UBE3C. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Chicken (87%), Bovine (89%)|