|Full Name||ubiquitin protein ligase E3 component n-recognin 2|
|Product Description||Rabbit Polyclonal antibody to UBR2 (ubiquitin protein ligase E3 component n-recognin 2)|
|Background||Proteolysis by the ubiquitin-proteasome system controls the concentration of many regulatory proteins. The selectivity of ubiquitylation is determined by ubiquitin E3 ligases, which recognize the substrate's destabilization signal, or degron. The E3 ligase UBR2 participates in the N-end rule pathway, which targets proteins bearing an N-terminal degron, or N-degron (Kwon et al., 2003 [PubMed 14585983]).[supplied by OMIM]|
|Synonyms||C6orf133 antibody, DKFZp686C08114 antibody, FLJ36357 antibody, KIAA0349 antibody, MGC71112 antibody, RP3-392M17.3 antibody, bA49A4.1 antibody, dJ242G1.1 antibody, dJ392M17.3 antibody, UBR2 antibody, E3 ubiquitin-protein ligase UBR2 antibody, ubiquitin-protein ligase E3-alpha-2 antibody, ubiquitin-protein ligase E3-alpha-II antibody, ubiquitin protein ligase E3 component n-recognin 2 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human UBR2. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Mouse, Rat, Bovine|
|Predict Reactivity Note||Human (100%), Mouse (93%), Rat (92%), Bovine (95%)|