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1 .GTX632673 UCP1 antibody [GT635]

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UCP1 antibody [GT635]


  • Host / ClonalityMouse Monoclonal
  • Clone NameGT635
  • ApplicationsWB
  • Species reactivityMouse, Pig
  • Publication  ( 1 )
Cat No: GTX632673
Package Price Qty
25 μlUSD 119.00
100 μlUSD 319.00
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  • Anti-UCP1 antibody [GT635] used in Western Blot (WB). GTX632673
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  • Datasheet
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  • Protocol & MSDS
  • Application Information: UCP1 antibody [GT635]

Catalog Number GTX632673
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( 0 )
Publication ( 1 )
Product Name UCP1 antibody [GT635]
See all UCP1 products
ApplicationsWB
Application Note
Suggested dilutionReference
Western Blot (WB)1:500-1:3000* Y
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
Predicted Target Size33 kDa (note)
Positive Controlsmouse brown adipose
Form SuppliedLiquid
Concentration1 mg/ml (Please refer to the vial label for the specific concentration)
PurificationAffinity purified by Protein A.

  • Specifications: UCP1 antibody [GT635]

Full Nameuncoupling protein 1 (mitochondrial, proton carrier)
BackgroundMitochondrial uncoupling proteins (UCP) are members of the family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat. [provided by RefSeq]
Synonymsuncoupling protein 1 (mitochondrial, proton carrier) Antibody , SLC25A7 Antibody , UCP Antibody
Cellular LocalizationMitochondrion inner membrane; Multi-pass membrane protein
HostMouse
ClonalityMonoclonal
Clone NameGT635
IsotypeIgG2b
ImmunogenCarrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human UCP1. The exact sequence is proprietary.
Antigen SpeciesHuman
Species ReactivityMouse, Pig
Predicted Cross Reactivity species Predicted cross-reactivity:
    Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
    Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
Human, Rat
Predict Reactivity NoteHuman (100%), Rat (100%)
ConjugationUnconjugated

  • Storage Conditions: UCP1 antibody [GT635]

Storage BufferPBS
Storage InstructionKeep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
NotesFor In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
ResearchArea
  • Cancer > Type of cancer > Thyroid
  • Disease Related > Atherosclerosis
  • Disease Related > Cardiovascular > Heart > Heart disease
  • Disease Related > Cardiovascular > Vessels
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UCP1 antibody [GT635] validated data
  • Anti-UCP1 antibody [GT635] used in Western Blot (WB). GTX632673
    • GTX632673 WB Image
      Mouse tissue extract (50 μg) was separated by 12% SDS-PAGE, and the membrane was blotted with UCP1 antibody (GTX632673) diluted at 1:1000.
      Top
  • Anti-UCP1 antibody [GT635] used in Western Blot (WB). GTX632673
    • GTX632673 WB Image
      Mouse tissue extract (50 μg) was separated by 12% SDS-PAGE, and the membrane was blotted with UCP1 antibody (GTX632673) diluted at 1:1000.
      Top
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  • Reference for UCP1 antibody [GT635]
Application References Application Reactivity
Zheng Q et al. Reconstitution of UCP1 using CRISPR/Cas9 in the white adipose tissue of pigs decreases fat deposition and improves thermogenic capacity. Proc Natl Acad Sci U S A 114 (45):E9474-E9482 (2017). WB Pig
Target Bioinfo/ Predicted Isoform Cross Reactivity
SpeciesGene nameGene IDSwissProtOMIMIsoform (mRNA)Protein Accession#MW
Homo sapiensUCP17350P25874113730, 601665NM_021833NP_06860533.01

Cross-react Bioinfo
SpeciesGene nameGene IDSwissProtIsoform (mRNA)Protein Accession#MW
Mus musculusUcp122227P12242NM_009463NP_03348933.25
Rattus norvegicusUcp124860P04633NM_012682NP_03681433.22
    *MSDS
    MSDS-PBS.pdf
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