|Full Name||solute carrier family 25, member 27|
|Product Description||Rabbit Polyclonal antibody to UCP4 (solute carrier family 25, member 27)|
|Background||Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. Transcripts of this gene are only detected in brain tissue and are specifically modulated by various environmental conditions. [provided by RefSeq]|
|Synonyms||FLJ33552 antibody, UCP4 antibody, SLC25A27 antibody, mitochondrial uncoupling protein 4 antibody, uncoupling protein 4 antibody, UCP 4 antibody, solute carrier family 25, member 27 antibody|
|Cellular Localization||Mitochondrion inner membrane; Multi-pass membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human UCP4. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Dog, Pig, Sheep, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (93%), Rat (95%), Dog (93%), Pig (90%), Sheep (92%), Rhesus Monkey (98%), Bovine (92%)|