|Full Name||ubiquitin fusion degradation 1 like (yeast)|
|Product Description||Rabbit Polyclonal antibody to UFD1L (ubiquitin fusion degradation 1 like (yeast))|
|Background||The protein encoded by this gene forms a complex with two other proteins, NPL4 and VCP, that is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]|
|Synonyms||UFD1 antibody, UFD1L antibody, UB fusion protein 1 antibody, ubiquitin fusion degradation protein 1 homolog antibody, ubiquitin fusion degradation 1 like (yeast) antibody|
|Cellular Localization||Nucleus (By similarity) , Cytoplasm , cytosol |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human UFD1L. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Zebrafish, Xenopus laevis, Chicken, Rhesus Monkey|
|Predict Reactivity Note||Mouse (98%), Rat (97%), Zebrafish (84%), Xenopus laevis (88%), Chicken (92%), Rhesus Monkey (99%)|