|Full Name||UDP glucuronosyltransferase 1 family, polypeptide A|
|Product Description||Rabbit Polyclonal antibody to UGT1A (UDP glucuronosyltransferase 1 family, polypeptide A)|
|Background||This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenols. [provided by RefSeq]|
|Synonyms||HLUGP4 antibody, LUGP4 antibody, UDPGT antibody, UDPGT 1-9 antibody, UGT1-09 antibody, UGT1AI antibody, UGT1A9 antibody, UDP-glucuronosyltransferase 1-I antibody, "UDP glycosyltransferase 1 family, polypeptide A9 antibody", UDP-glucuronosyltransferase 1-9 antibody, UDP-glucuronosyltransferase 1A9 antibody, "UDP glucuronosyltransferase 1 family, polypeptide A9 antibody"|
|Cellular Localization||Microsome , Endoplasmic reticulum membrane; Single-pass membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human UGT1A. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Rat (89%), Sheep (89%)|