|Full Name||uridine monophosphate synthetase|
|Product Description||Rabbit Polyclonal antibody to UMPS (uridine monophosphate synthetase)|
|Background||This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants. [provided by RefSeq]|
|Synonyms||OPRT antibody, UMPS antibody, UMP synthase antibody, OPRTase antibody, uridine 5'-monophosphate synthase antibody, OMPdecase antibody, orotidine 5'-phosphate decarboxylase antibody, orotate phosphoribosyltransferase antibody, uridine monophosphate synthetase antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human UMPS. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (90%), Rat (92%), Chicken (81%), Rhesus Monkey (98%), Bovine (89%)|