|Full Name||uracil-DNA glycosylase|
|Product Description||Rabbit Polyclonal antibody to UNG (uracil-DNA glycosylase)|
|Background||This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. [provided by RefSeq]|
|Synonyms||DGU antibody, DKFZp781L1143 antibody, HIGM4 antibody, UDG antibody, UNG1 antibody, UNG15 antibody, UNG2 antibody, UNG antibody, uracil-DNA glycosylase 1, uracil-DNA glycosylase 2 antibody, uracil-DNA glycosylase antibody|
|Cellular Localization||Isoform 1: Mitochondrion , Isoform 2: Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human UNG. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Xenopus laevis, Chicken, Chimpanzee, Bovine|
|Predict Reactivity Note||Mouse (91%), Rat (91%), Xenopus laevis (81%), Chicken (87%), Chimpanzee (100%), Bovine (97%)|