|Full Name||fermitin family member 3|
|Product Description||Rabbit Polyclonal antibody to URP2 (fermitin family homolog 3 (Drosophila))|
|Background||Kindlins are a small family of proteins that mediate protein-protein interactions involved in integrin activation and thereby have a role in cell adhesion, migration, differentiation, and proliferation. The protein encoded by this gene has a key role in the regulation of hemostasis and thrombosis. This protein may also help maintain the membrane skeleton of erythrocytes. Mutations in this gene cause the autosomal recessive leukocyte adhesion deficiency syndrome-III (LAD-III). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq]|
|Synonyms||KIND3 antibody, MGC10966 antibody, MIG-2 antibody, MIG2B antibody, UNC112C antibody, URP2 antibody, URP2SF antibody, FERMT3 antibody, MIG2-like protein antibody, UNC-112 related protein 2 antibody, fermitin family homolog 3 antibody, kindlin 3 antibody, unc-112-related protein 2 antibody, fermitin family member 3 antibody|
|Cellular Localization||Cytoplasm (Probable) , Cell membrane; Peripheral membrane protein; Cytoplasmic side (By similarity) |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human URP2. The exact sequence is proprietary.|
|Species Reactivity||Human, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Mouse (88%), Bovine (93%)|