|Full Name||ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)|
|Product Description||Rabbit Polyclonal antibody to USP14 (ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase))|
|Background||This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age followed by hindlimb paralysis and death by 6 to 10 weeks of age. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]|
|Synonyms||TGT antibody, USP14 antibody, ubiquitin-specific-processing protease 14 antibody, deubiquitinating enzyme 14 antibody, ubiquitin specific protease 14 (tRNA-guanine transglycosylase) antibody, ubiquitin thioesterase 14 antibody, ubiquitin-specific processing protease 14 antibody, ubiquitin thiolesterase 14 antibody, ubiquitin carboxyl-terminal hydrolase 14 antibody, tRNA-guanine transglycosylase, 60-kD subunit antibody, ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) antibody|
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human USP14. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Zebrafish, Rabbit, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Zebrafish (81%), Rabbit (96%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (97%)|