| Full Name | ubiquitin specific peptidase 5 (isopeptidase T) |
| Background | Ubiquitin (see MIM 191339)-dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse cellular functions as maintenance of chromatin structure, receptor function, and degradation of abnormal proteins. A late step of the process involves disassembly of the polyubiquitin chains on degraded proteins into ubiquitin monomers. USP5 disassembles branched polyubiquitin chains by a sequential exo mechanism, starting at the proximal end of the chain (Wilkinson et al., 1995 [PubMed 7578059]).[supplied by OMIM] |
| Synonyms | ISOT antibody, USP5 antibody, isopeptidase T antibody, ubiquitin thiolesterase 5 antibody, deubiquitinating enzyme 5 antibody, ubiquitin isopeptidase T antibody, ubiquitin specific protease 5 (isopeptidase T) antibody, ubiquitin-specific-processing protease 5 antibody, ubiquitin-specific protease-5 (ubiquitin isopeptidase T) antibody, ubiquitin thioesterase 5 antibody, ubiquitin carboxyl-terminal hydrolase 5 antibody, ubiquitin specific peptidase 5 (isopeptidase T) antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant protein encompassing a sequence within the N-terminus region of human USP5. The exact sequence is proprietary. |
| Antigen Species | Human |
| Species Reactivity | Human, Mouse |
Predicted Cross Reactivity species  Predicted cross-reactivity:
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
| Rat, Rhesus Monkey, Bovine |
| Predict Reactivity Note | Rat (96%), Rhesus Monkey (100%), Bovine (97%) |
| Conjugation | Unconjugated |