Ubiquilin-1 antibody [N1C1]
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||63 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||ubiquilin 1|
|Product Description||Rabbit polyclonal antibody to Ubiquilin-1 (ubiquilin 1)|
|Background||This gene encodes an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||DA41 antibody, DSK2 antibody, FLJ90054 antibody, PLIC-1 antibody, UBQN antibody, XDRP1 antibody, UBQLN1 antibody, protein linking IAP with cytoskeleton 1 antibody, hPLIC-1 antibody, ubiquilin-1 antibody, ubiquilin 1 antibody|
|Cellular Localization||Cytoplasm , Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Ubiquilin-1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Sheep, Bovine|
|Predict Reactivity Note||Mouse (90%), Rat (90%), Sheep (96%), Bovine (95%)|