|Full Name||ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2|
|Product Description||Rabbit polyclonal antibody to V-ATPase C2 (ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2)|
|Background||This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A,three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain C subunit isoforms. [provided by RefSeq]|
|Synonyms||ATP6C2 antibody, VMA5 antibody, ATP6V1C2 antibody, vacuolar proton pump subunit C 2 antibody, V-ATPase C2 subunit antibody, V-type proton ATPase subunit C 2 antibody, V-ATPase subunit C 2 antibody, "ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human V-ATPase C2. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Bovine|
|Predict Reactivity Note||Mouse (89%), Rat (90%), Bovine (92%)|