|Full Name||ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D|
|Product Description||Rabbit Polyclonal antibody to V-ATPase D (ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D)|
|Background||This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes the V1 domain D subunit protein. [provided by RefSeq]|
|Synonyms||ATP6M antibody, VATD antibody, VMA8 antibody, ATP6V1D antibody, V-type proton ATPase subunit D antibody, vacuolar proton pump subunit D antibody, ATPase, H+ transporting, lysosomal (vacuolar proton pump) antibody, vacuolar ATP synthase subunit D antibody, V-ATPase D subunit antibody, V-ATPase 28 kDa accessory protein antibody, vacuolar proton pump delta polypeptide antibody, ATPase, H+ transporting lysosomal, member M antibody, vacuolar H-ATPase subunit D antibody, vacuolar proton pump D subunit antibody, vacuolar proton-ATPase subunit D antibody, H(+)-transporting two-sector ATPase, subunit M antibody, V-ATPase subunit D antibody, ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human V-ATPase D. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Zebrafish, Rabbit, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (98%), Zebrafish (87%), Rabbit (98%), Chicken (93%), Rhesus Monkey (100%), Bovine (98%)|