| Full Name | ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F |
| Background | This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is the V1 domain F subunit protein. [provided by RefSeq] |
| Synonyms | ATP6S14 antibody, MGC117321 antibody, MGC126037 antibody, MGC126038 antibody, VATF antibody, Vma7 antibody, ATP6V1F antibody, vacuolar ATP synthase subunit F antibody, H(+)-transporting two-sector ATPase, 14kD subunit antibody, ATPase, vacuolar, 14 kD antibody, V-ATPase subunit F antibody, V-ATPase F subunit antibody, vacuolar proton pump subunit F antibody, vacuolar proton pump F subunit antibody, V-type proton ATPase subunit F antibody, adenosinetriphosphatase 14k chain antibody, V-ATPase 14 kDa subunit antibody, ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human V-ATPase F. The exact sequence is proprietary. |
| Antigen Species | Human |
| Species Reactivity | Human |
Predicted Cross Reactivity species  Predicted cross-reactivity:
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
| Mouse, Rat, Zebrafish, Xenopus laevis, Chimpanzee, Bovine |
| Predict Reactivity Note | Mouse (98%), Rat (98%), Zebrafish (82%), Xenopus laevis (83%), Chimpanzee (100%), Bovine (99%) |
| Conjugation | Unconjugated |