Full Name | vascular cell adhesion molecule 1 |
Background | This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq] |
Synonyms | CD106 antibody, DKFZp779G2333 antibody, INCAM-100 antibody, MGC99561 antibody, VCAM1 antibody, vascular cell adhesion protein 1 antibody, CD106 antigen antibody, vascular cell adhesion molecule 1 antibody |
Cellular Localization | Membrane; Single-pass type I membrane protein |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Recombinant protein encompassing a sequence within the center region of human VCAM1 / CD106. The exact sequence is proprietary. |
Antigen Species | Human |
Species Reactivity | Human |
Predicted Cross Reactivity species Predicted cross-reactivity: Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive. Please note that we are only able to guarantee products to work in applications and species in which they have been tested. | Dog, Pig, Rabbit, Bovine |
Predict Reactivity Note | Dog (84%), Pig (80%), Rabbit (86%), Bovine (82%) |
Conjugation | Unconjugated |