|Applications||ICC/IF, IHC-P, IP, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||89 kDa (note)
|Positive Controls||A431 , H1299 , mouse brain , rat brain , A549 , H1299 , HCT-116|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||valosin containing protein|
|Product Description||Rabbit Polyclonal antibody to VCP (valosin containing protein)|
|Background||The protein encoded by this gene is a member of a family that includes putative ATP-binding proteins involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. This protein, as a structural protein, is associated with clathrin, and heat-shock protein Hsc70, to form a complex. It has been implicated in a number of cellular events that are regulated during mitosis, including homotypic membrane fusion, spindle pole body function, and ubiquitin-dependent protein degradation. [provided by RefSeq]|
|Synonyms||IBMPFD antibody, MGC131997 antibody, MGC148092 antibody, MGC8560 antibody, TERA antibody, p97 antibody, VCP antibody, yeast Cdc48p homolog antibody, 15S Mg(2+)-ATPase p97 subunit antibody, TER ATPase antibody, transitional endoplasmic reticulum ATPase antibody, valosin-containing protein antibody, valosin containing protein antibody|
|Cellular Localization||Cytoplasm , cytosol , Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human VCP. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Zebrafish, Pig, Chicken, Chimpanzee, Bovine|
|Predict Reactivity Note||Zebrafish (92%), Pig (100%), Chicken (99%), Chimpanzee (100%), Bovine (100%)|