VDP/p115 antibody [C3], C-term
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||108 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||USO1 vesicle docking protein homolog (yeast)|
|Product Description||Rabbit Polyclonal antibody to VDP/p115 (USO1 homolog, vesicle docking protein (yeast))|
|Background||The protein encoded by this gene is a peripheral membrane protein which recycles between the cytosol and the Golgi apparatus during interphase. It is regulated by phosphorylation: dephosphorylated protein associates with the Golgi membrane and dissociates from the membrane upon phosphorylation. Ras-associated protein 1 recruits this protein to coat protein complex II (COPII) vesicles during budding from the endoplasmic reticulum, where it interacts with a set of COPII vesicle-associated SNAREs to form a cis-SNARE complex that promotes targeting to the Golgi apparatus. Transport from the ER to the cis/medial Golgi compartments requires the action of this gene product, GM130 and giantin in a sequential manner. [provided by RefSeq]|
|Synonyms||P115 antibody, TAP antibody, VDP antibody, USO1 antibody, vesicle-docking protein antibody, vesicle docking protein p115 antibody, transcytosis associated protein antibody, protein USO1 homolog antibody, "USO1 homolog, vesicle docking protein antibody", general vesicular transport factor p115 antibody, USO1 vesicle docking protein homolog (yeast) antibody|
|Cellular Localization||Cytoplasm , cytosol , Golgi apparatus membrane; Peripheral membrane protein |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human VDP/p115. The exact sequence is proprietary.|