Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Positive Controls||293T , A431 , HeLa , HepG2 , Neuro2A , CD830 , NIH-3T3 , Raw264.7 , C2C12|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||USO1 vesicle transport factor|
|Product Description||Rabbit Polyclonal antibody to VDP/p115 (USO1 vesicle transport factor)|
|Background||The protein encoded by this gene is a peripheral membrane protein which recycles between the cytosol and the Golgi apparatus during interphase. It is regulated by phosphorylation: dephosphorylated protein associates with the Golgi membrane and dissociates from the membrane upon phosphorylation. Ras-associated protein 1 recruits this protein to coat protein complex II (COPII) vesicles during budding from the endoplasmic reticulum, where it interacts with a set of COPII vesicle-associated SNAREs to form a cis-SNARE complex that promotes targeting to the Golgi apparatus. Transport from the ER to the cis/medial Golgi compartments requires the action of this gene product, GM130 and giantin in a sequential manner. [provided by RefSeq]|
|Synonyms||VDP Antibody, USO1 Antibody, TAP Antibody, USO1 vesicle transport factor Antibody, P115 Antibody|
|Cellular Localization||Cytoplasm , cytosol , Golgi apparatus membrane; Peripheral membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human VDP/p115. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Bovine (87%)|