|Full Name||kinase insert domain receptor|
|Product Description||Rabbit Polyclonal antibody to VEGFR-2 (phospho Tyr1175)|
|Background||Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]|
|Synonyms||kinase insert domain receptor Antibody , FLK1 Antibody , CD309 Antibody , VEGFR Antibody , KDR Antibody , VEGFR2 Antibody|
|Specificity||Recognizes endogenous levels of VEGFR2 (pY1175) protein.|
|Target||VEGFR-2 (phospho Tyr1175)|
|Immunogen||KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human VEGFR2 (pY1175). The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Rat(100%)|