|Full Name||vacuolar protein sorting 4 homolog B (S. cerevisiae)|
|Product Description||Rabbit polyclonal antibody to VPS4B (vacuolar protein sorting 4 homolog B (S. cerevisiae))|
|Background||The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 18; the gene for the other resides on chromosome 16. [provided by RefSeq]|
|Synonyms||SKD1 antibody, SKD1B antibody, VPS4-2 antibody, VPS4B antibody, cell migration-inducing 1 antibody, vacuolar protein sorting-associated protein 4B antibody, suppressor of K+ transport defect 1 antibody, vacuolar protein sorting 4B antibody, cell migration-inducing gene 1 protein antibody, suppressor of K(+) transport growth defect 1 antibody, vacuolar protein sorting 4 homolog B (S. cerevisiae) antibody|
|Cellular Localization||Prevacuolar compartment membrane; Peripheral membrane protein , Late endosome membrane; Peripheral membrane protein (Probable) |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human VPS4B. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Zebrafish, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (96%), Rat (96%), Zebrafish (88%), Chicken (89%), Rhesus Monkey (99%), Bovine (96%)|