|Full Name||nicotinamide phosphoribosyltransferase|
|Product Description||Rabbit Polyclonal antibody to Visfatin (nicotinamide phosphoribosyltransferase)
|Background||This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It also activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity. This gene has a pseudogene on chromosome 10. [provided by RefSeq]|
|Synonyms||1110035O14Rik antibody, DKFZp666B131 antibody, MGC117256 antibody, PBEF antibody, PBEF1 antibody, VF antibody, VISFATIN antibody, NAMPT antibody, NAmPRTase antibody, pre-B-cell colony enhancing factor 1 antibody, pre-B cell-enhancing factor antibody, pre-B-cell colony-enhancing factor 1 antibody, nicotinamide phosphoribosyltransferase antibody|
|Cellular Localization||Cytoplasm |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Visfatin. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Xenopus laevis, Pig, Chicken, Bovine|
|Predict Reactivity Note||Rat (87%), Xenopus laevis (87%), Pig (97%), Chicken (84%), Bovine (87%)|