|Full Name||vitamin D (1,25- dihydroxyvitamin D3) receptor|
|Product Description||Rabbit Polyclonal antibody to Vitamin D receptor (vitamin D (1,25- dihydroxyvitamin D3) receptor)|
|Background||This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq]|
|Synonyms||NR1I1 antibody, VDR antibody, nuclear receptor subfamily 1 group I member 1 antibody, "1,25-dihydroxyvitamin D3 receptor antibody", vitamin D nuclear receptor variant 1 antibody, vitamin D3 receptor antibody, "vitamin D (1,25- dihydroxyvitamin D3) receptor antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Vitamin D Receptor. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Pig (82%), Bovine (87%)|