|Full Name||vitamin D (1,25- dihydroxyvitamin D3) receptor|
|Product Description||Goat polyclonal antibody to VDR|
|Background||Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Regulates transcription of hormone sensitive genes via its association with the WINAC complex, a chromatin-remodeling complex. Recruited to promoters via its interaction with the WINAC complex subunit BAZ1B/WSTF, which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis. |
|Synonyms||VDR, vitamin D (1,25 dihydroxyvitamin D3) receptor, vitamin D (1,25- dihydroxyvitamin D3) receptor, HGNC:12679, vitamin D (1,25dihydroxyvitamin D3) receptor, NR1I1, vitamin D (1,25-dihydroxyvitamin D3) receptor|
|Specificity||This antibody is specific for VDR.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.