|Applications||IHC-P, IP, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||70 kDa (note)
|Positive Controls||Jurkat , Raji , K562 , THP-1 , HL-60 , NCI-H929|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||WW domain binding protein 11|
|Product Description||Rabbit Polyclonal antibody to WBP11 (WW domain-binding protein 11)|
|Background||This gene encodes a nuclear protein, which colocalizes with mRNA splicing factors and intermediate filament-containing perinuclear networks. This protein has 95% amino acid sequence identity to the mouse Wbp11 protein. It contains two proline-rich regions that bind to the WW domain of Npw38, a nuclear protein, and thus this protein is also called Npw38-binding protein NpwBP. The Npw38-NpwBP complex may function as a component of an mRNA factory in the nucleus. [provided by RefSeq]|
|Synonyms||DKFZp779M1063 antibody, NPWBP antibody, SIPP1 antibody, WBP11 antibody, "splicing factor, PQBP1 and PP1 interacting antibody", SH3 domain-binding protein SNP70 antibody, splicing factor that interacts with PQBP-1 and PP1 antibody, WW domain-binding protein 11 antibody, Npw38-binding protein NpwBP antibody, WW domain binding protein 11 antibody|
|Cellular Localization||Nucleus , Cytoplasm |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human WBP11. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Xenopus laevis, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Xenopus laevis (84%), Rhesus Monkey (99%), Bovine (99%)|