|Full Name||WD repeat domain 77|
|Product Description||Rabbit Polyclonal antibody to WDR77 (WD repeat domain 77)|
|Background||WDR77 is a component of the 20S PRMT5 (MIM 604045)-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins (see MIM 601061). This modification targets Sm proteins to the survival of motor neurons (SMN) complex (see MIM 600354) for assembly into small nuclear ribonucleoprotein core particles (Friesen et al., 2002 [PubMed 11756452]).[supplied by OMIM]|
|Synonyms||MEP-50 antibody, MEP50 antibody, MGC2722 antibody, Nbla10071 antibody, RP11-552M11.3 antibody, p44 antibody, p44/Mep50 antibody, WDR77 antibody, androgen receptor cofactor p44 antibody, WD repeat-containing protein 77 antibody, methylosome protein 50 antibody, WD repeat domain 77 antibody|
|Cellular Localization||Nucleus , Cytoplasm |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human WDR77. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Mouse (87%), Rat (87%), Rhesus Monkey (97%), Chimpanzee (99%), Bovine (89%)|