|Full Name||WAS/WASL interacting protein family, member 1|
|Product Description||Goat polyclonal antibody to WIPF1|
|Background||May have direct activity on the actin cytoskeleton. Induces actin polymerization and redistribution. Contributes with NCK1 and GRB2 in the recruitment and activation of WASL. May participate in regulating the subcellular localization of WASL, resulting in the disassembly of stress fibers in favor of filopodia formation (By similarity). Plays an important role in the intracellular motility of vaccinia virus by functioning as an adapter for recruiting WASL to vaccinia virus. |
|Synonyms||WIP, WiskottAldrich syndrome protein interacting protein, WAS/WASL interacting protein family, member 1, MGC111041, WASPIP, PRPL2, Wiskott-Aldrich syndrome protein interacting protein, WIPF1, PRPL-2, WAS/WASL interacting protein family, member1, PRPL 2|
|Cellular Localization||Vesicle surfaces and along actin tails. Co-localized with actin stress fibers. When co-expressed with WASL, no longer associated with actin filaments but accumulated in perinuclear and cortical areas like WASL. |
|Specificity||This antibody is specific for WIPF1.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Dog|