|Applications||ICC/IF, IHC, IHC-P, WB|
Not tested in other applications.
| Immunohistochemistry||Assay-dependent dilution
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||39 kDa (note)
|Positive Controls||293T , A431 , HeLa , HepG2 , mouse heart|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||wingless-type MMTV integration site family, member 11|
|Product Description||Rabbit Polyclonal antibody to WNT11 (wingless-type MMTV integration site family, member 11)|
|Background||The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 97%, 85%, and 63% amino acid identity with mouse, chicken, and Xenopus Wnt11 protein, respectively. This gene may play roles in the development of skeleton, kidney and lung, and is considered to be a plausible candidate gene for High Bone Mass Syndrome. [provided by RefSeq]|
|Synonyms||HWNT11 antibody, MGC141946 antibody, MGC141948 antibody, WNT11 antibody, protein Wnt-11 antibody, "wingless-type MMTV integration site family, member 11 antibody"|
|Cellular Localization||Secreted , extracellular space , extracellular matrix |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human WNT11. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Xenopus laevis, Rabbit, Chicken, Bovine|
|Predict Reactivity Note||Rat (96%), Xenopus laevis (81%), Rabbit (97%), Chicken (85%), Bovine (98%)|