|Full Name||WW domain containing E3 ubiquitin protein ligase 1|
|Product Description||Rabbit Polyclonal antibody to WWP1 (WW domain containing E3 ubiquitin protein ligase 1)|
|Background||WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 4 tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain. The encoded protein belongs to a family of NEDD4-like proteins, which are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes. Alternative splicing of this gene generates at least 6 transcript variants; however, the full length nature of these transcripts has not been defined. [provided by RefSeq]|
|Synonyms||WW domain containing E3 ubiquitin protein ligase 1 Antibody , hSDRP1 Antibody , Tiul1 Antibody , AIP5 Antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human WWP1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Rat, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Human (100%), Rat (99%), Chicken (96%), Rhesus Monkey (99%), Bovine (99%)|