Cancer Research Cell Death Cancer Stem Cell Cancer Immune Checkpoints Cancer-related Glycolysis Tumor Suppressor Genes Oncogenes

Cancer Research

Every year there are four million new cases of cancer diagnosed in the world, with over eight million cancer-related deaths. There are over 100 different types of cancer, with often significant genotypic and phenotypic heterogeneity even among tumors of the same kind. Research is one of the best weapons to oppose this scourge, and great progress has been made in cancer diagnosis, treatment, and prevention. In addition, scientists have made enormous strides dissecting the mechanisms and pathways that drive carcinogenesis and metastasis, and in offering approaches as to how these processes can be potentially targeted for therapeutic purposes.

 

  • Oncogenes 
  • Oncogenes
  • The products of metazoan cell proto-oncogenes are generally key constituents of the cell signaling and gene ...
  • see more
  • Tumor Suppressor Genes 
  • Tumor Suppressor Genes
  • Tumor suppressor gene products act as barriers to block cells from proceeding down the path to cancer. In contrast to the ...
  • see more
  • Cancer Metabolism 
  • Cancer Metabolism
  • Nearly a century ago, Otto Warburg found that cancer cells can shift their energy production to aerobic glycolysis ...
  • see more
  • Cancer Stem Cells 
  • Cancer Stem Cells
  • Cancer stem cells (CSCs) are being increasingly recognized as the key determinative cells of malignancies ...
  • see more
  • Cell Death 
  • Cell Death
  • Cell death occurs when a cell is no longer able to sustain essential life functions. Cells can die through one of several ...
  • see more
  • Cancer Immune Checkpoints 
  • Hypoxia Markers
  • The development of complex anatomical and physiological systems to maintain oxygen homeostasis was an essential ...
  • see more
  • Angiogenesis 
  • Angiogenesis
  • Angiogenesis entails the generation of new blood vessels from pre-existing vasculature. It is an intricate process tightly ...
  • see more