Datasheet
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Date : 2018/11/14
Catalog Number GTX34794                                     Package:100 μg         
Product Name Interferon gamma antibody [IFNG/466]
Full Nameinterferon, gamma
SynonymsIFI Antibody , interferon, gamma Antibody , IFG Antibody , IFNG Antibody
SpecificityRecognizes a protein of 20-25kDa, identified as human interferon. This MAb is specific to human IFN-g and recognizes both recombinant and native human IFN-gamma. T lymphocytes and NK cells mainly produce IFN-g. It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses, including the activation, growth and differentiation of T cell, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. It has weak anti-viral and anti-proliferative activity, and potentiates the antiviral and anti-tumor effects of IFN-a/b (type I interferon).
BackgroundThis gene encodes a member of the type II interferon family. The protein encoded is a soluble cytokine with antiviral, immunoregulatory and anti-tumor properties and is a potent activator of macrophages. Mutations in this gene are associated with aplastic anemia.[provided by RefSeq, Nov 2009]
HostMouse
ClonalityMonoclonal
Clone NameIFNG/466
IsotypeIgG2b
Light ChainKappa
ImmunogenPurified recombinant human IFN-gamma
Antigen SpeciesHuman
Species ReactivityHuman
ApplicationsIHC-P
Application NoteIHC-P:1-2ug/ml for 30 min at RT.
Predicted Target Size19 kDa
ConjugationUnconjugated
Form SuppliedLiquid
PurificationAb purified from Bioreactor Concentrate by Protein A/G
Storage BufferPrepared in 10mM PBS with 0.05% BSA and 0.05% azide.
Storage InstructionStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20° C or below. Avoid multiple freeze-thaw cycles.
NotesFor In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
ResearchAreaCancer > Apoptosis > Inflammatory cell > Neutrophil
Cancer > Apoptosis > Metastasis and Invasion > Invasion
Cancer > Apoptosis > Metastasis and Invasion > Metastasis > Lymphatic
Anti-Interferon gamma antibody [IFNG/466] used in IHC (Formalin-fixed paraffin-embedded sections). GTX34794
  • GTX34794 IHC-P Image
  • Formalin-fixed, paraffin-embedded human Renal Cell Carcinoma stained with Interferon gamma Monoclonal Antibody (IFNG/466)
Anti-Interferon gamma antibody [IFNG/466] used in IHC (Formalin-fixed paraffin-embedded sections). GTX34794
  • GTX34794 IHC-P Image
  • Formalin-fixed, paraffin-embedded human Testicular Carcinoma stained with Interferon gamma Monoclonal Antibody (IFNG/466)
Anti-Interferon gamma antibody [IFNG/466] used in IHC (Formalin-fixed paraffin-embedded sections). GTX34794
  • GTX34794 IHC-P Image
  • Formalin-fixed, paraffin-embedded human Renal Cell Carcinoma stained with Interferon gamma Monoclonal Antibody (IFNG/466)