Human 

galanin receptor 2 antibody
Product Name Cat No Package Price Special Price Availability Qty
galanin receptor 2 antibody GTX100320 100μl USD 289.00 - next day delivery
galanin receptor 2 antibody GTX100320 25μl USD 79.00 - next day delivery


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Catalog NumberGTX100320
Product Namegalanin receptor 2 antibody
Full Namegalanin receptor 2
SynonymsGALR2|GALNR2|MGC125983|MGC125984|galanin receptor 2
Product DescriptionRabbit polyclonal antibody to galanin receptor 2 (galanin receptor 2)
BackgroundGalanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis. It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility. The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7-transmembrane family of G protein-coupled receptors. GALR2 interacts with the N-terminal residues of the galanin peptide. The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway (via Gq), in contrast to GALR1, which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi. However, it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simultaneously activate 2 independent signal transduction pathways. [provided by RefSeq]
HostRabbit
ClonalityPolyclonal
ImmunogenSynthetic peptide contain a sequence corresponding to a region within amino acids 212 and 277 of galanin receptor 2
Antigen SpeciesHuman
Species Cross Reactivityhuman - Not yet tested in other species
Tested ApplicationsWestern blot. The usefulness of this product in other applications has not been determined.
Application NoteSuggested starting dilutions are as follows. WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Positive Controls293T | A431 | H1299 | HeLaS3 | HepG2 | Molt-4 | Raji
Targetgalanin receptor 2
Predicted Target Size(KDa)42
Cellular LocalizationCell membrane; Multi-pass membrane protein
Form SuppliedLiquid
Concentration1 mg/ml
PurificationPurified by antigen-affinity chromatography.
Storage Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage InstructionKeep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
NotesFor In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
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