| Catalog Number | GTX109736 |
| Product Name | Aconitase 2 antibody |
| Full Name | aconitase 2, mitochondrial |
| Product Description | Rabbit polyclonal antibody to ACO2 (aconitase 2, mitochondrial) |
| Synonyms | ACONM | MGC20605 | MGC33908 |
| Background | The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification. [provided by RefSeq] |
| Clonality | Polyclonal |
| Host | Rabbit |
| Immunogen | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 415 and 665 of Human ACO2 |
| Antigen Species | Human |
| Tested Applications | WB. The usefulness of this product in other applications has not been determined. |
| Application Note | Suggested starting dilutions are as follows. WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. |
| Specificity | This antibody is specific to the Human ACO2 protein. |
| Species Cross Reactivity | Human - Not yet tested in other species |
| Positive Controls | 293T | A431 | H1299 | HeLa | HepG2 | Molt-4 | Raji |
| Target | ACO2 |
| Predicted Target Size(KDa) | 85.44 |
| Cellular Localization | Mitochondrion |
| Form Supplied | Liquid |
| Concentration | 0.82 mg/ml |
| Purification | Purified by antigen-affinity chromatography. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |