| Catalog Number | GTX110010 |
| Product Name | oral-facial-digital syndrome 1 antibody |
| Full Name | oral-facial-digital syndrome 1 |
| Product Description | Rabbit polyclonal antibody to OFD1 (oral-facial-digital syndrome 1) |
| Synonyms | 71-7A | CXorf5 | MGC117039 | MGC117040 | SGBS2 |
| Background | This gene is located on the X chromosome and encodes a centrosomal protein. A knockout mouse model has been used to study the effect of mutations in this gene. The mouse gene is also located on the X chromosome, however, unlike the human gene it is not subject to X inactivation. Mutations in this gene are associated with oral-facial-digital syndrome type I and Simpson-Golabi-Behmel syndrome type 2. Many pseudogenes have been identified; a single pseudogene is found on chromosome 5 while as many as fifteen have been found on the Y chromosome. Alternatively spliced transcripts have been described for this gene but the biological validity of these transcripts has not been determined. [provided by RefSeq] |
| Clonality | Polyclonal |
| Host | Rabbit |
| Immunogen | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 136 and 387 of Human OFD1 |
| Antigen Species | Human |
| Tested Applications | WB. The usefulness of this product in other applications has not been determined. |
| Application Note | Suggested starting dilutions are as follows. WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. |
| Specificity | This antibody is specific to the Human OFD1 protein. |
| Species Cross Reactivity | Human - Not yet tested in other species |
| Positive Controls | 293T︱A431︱H1299︱HeLa︱HepG2︱Molt-4︱Raji |
| Target | OFD1 |
| Predicted Target Size(KDa) | 116.7 |
| Cellular Localization | Cytoplasm | Centrosome |
| Form Supplied | Liquid |
| Concentration | 0.96 mg/ml |
| Purification | Purified by antigen-affinity chromatography. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |