| Catalog Number | GTX101362 |
| Product Name | Actin antibody |
| Full Name | actin, alpha 1, skeletal muscle |
| Product Description | Rabbit polyclonal antibody to ACTA1 (actin, alpha 1, skeletal muscle) |
| Synonyms | ACTA | ASMA | CFTD | CFTD1 | CFTDM | MPFD | NEM1 | NEM2 | NEM3 |
| Background | The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects. [provided by RefSeq] |
| Clonality | Polyclonal |
| Host | Rabbit |
| Immunogen | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 129 of Human ACTA1 |
| Antigen Species | Human |
| Tested Applications | WB. The usefulness of this product in other applications has not been determined. |
| Application Note | Suggested starting dilutions are as follows. WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. |
| Specificity | This antibody is specific to the Human ACTA1 protein. |
| Species Cross Reactivity | Human - Not yet tested in other species |
| Positive Controls | Molt-4 | Raji |
| Target | ACTA1 |
| Predicted Target Size(KDa) | 42.06 |
| Cellular Localization | Cytoplasm | cytoskeleton |
| Form Supplied | Liquid |
| Concentration | 0.81 mg/ml |
| Purification | Purified by antigen-affinity chromatography. |
| Storage Buffer | 1XPBS, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |