| Catalog Number | GTX110516 |
|---|
| Product Name | TACC2 antibody |
|---|
| Full Name | transforming, acidic coiled-coil containing protein 2 |
|---|
| Synonyms | TACC2|AZU-1|ECTACC|transforming, acidic coiled-coil containing protein 2 |
|---|
| Product Description | Rabbit polyclonal antibody to TACC2 (transforming, acidic coiled-coil containing protein 2) |
|---|
| Background | Transforming acidic coiled-coil proteins are a conserved family of centrosome- and microtubule-interacting proteins that are implicated in cancer. This gene encodes a protein that concentrates at centrosomes throughout the cell cycle. This gene lies within a chromosomal region associated with tumorigenesis. Expression of this gene is induced by erythropoietin and is thought to affect the progression of breast tumors. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
|---|
| Host | Rabbit |
|---|
| Clonality | Polyclonal |
|---|
| Immunogen | Synthetic peptide contain a sequence corresponding to a region within amino acids 237 and 303 of TACC2 |
|---|
| Antigen Species | Human |
|---|
| Species Cross Reactivity | human - Not yet tested in other species |
|---|
| Predicted Cross Reactivity Species | mouse(100%), rat(100%) |
|---|
| Tested Applications | IHC (Formalin-fixed paraffin-embedded sections), Western blot. The usefulness of this product in other applications has not been determined. |
|---|
| Application Note | Suggested starting dilutions are as follows. WB: 1:500-1:3000,IHC-P: 1:100-1:500. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. |
|---|
| Positive Controls | 293T | A431 | H1299 | HeLaS3 | HepG2 | Molt-4 | Raji |
|---|
| Target | TACC2 |
|---|
| Predicted Target Size(KDa) | 119 |
|---|
| Cellular Localization | Cytoplasm | Nucleus | Centrosome |
|---|
| Form Supplied | Liquid |
|---|
| Concentration | 0.28 mg/ml |
|---|
| Purification | Purified by antigen-affinity chromatography. |
|---|
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
|---|
| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
|---|
| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
|---|