| Catalog Number | GTX102695 |
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| Product Name | P4HA2 antibody |
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| Full Name | procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide II |
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| Synonyms | P4HA2|-|prolyl 4-hydroxylase, alpha polypeptide II |
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| Product Description | Rabbit polyclonal antibody to P4HA2 (procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide II) |
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| Background | This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq] |
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| Host | Rabbit |
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| Clonality | Polyclonal |
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| Immunogen | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 86 and 436 of Human P4HA2 |
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| Antigen Species | Human |
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| Species Cross Reactivity | Human - Not yet tested in other species |
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| Predicted Cross Reactivity Species | mouse(93%), rat(93%), cow(94%) |
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| Tested Applications | Western blot. The usefulness of this product in other applications has not been determined. |
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| Application Note | Suggested starting dilutions are as follows. WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. |
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| Positive Controls | H1299 | HeLa |
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| Target | P4HA2 |
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| Predicted Target Size(KDa) | 61 |
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| Post-translation modification | Glycoprotein |
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| Cellular Localization | Endoplasmic reticulum lumen |
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| Form Supplied | Liquid |
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| Concentration | 2 mg/ml |
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| Purification | Affinity purified by Protein A. |
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| Storage Buffer | 1XPBS, 40% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
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| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20oC or below. Avoid multiple freeze-thaw cycles. |
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| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
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