| Catalog Number | GTX101557 |
| Product Name | mTOR antibody |
| Full Name | FK506 binding protein 12-rapamycin associated protein 1 |
| Product Description | Rabbit polyclonal antibody to FRAP1 (FK506 binding protein 12-rapamycin associated protein 1) |
| Synonyms | FLJ44809 | FRAP | FRAP2 | MTOR | RAFT1 | RAPT1 |
| Background | The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq] |
| Clonality | Polyclonal |
| Host | Rabbit |
| Immunogen | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 2386 and 2547 of Human FRAP1 |
| Antigen Species | Human |
| Tested Applications | WB. The usefulness of this product in other applications has not been determined. |
| Application Note | Suggested starting dilutions are as follows. WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. |
| Specificity | This antibody is specific to the Human FRAP1 protein. |
| Species Cross Reactivity | Human - Not yet tested in other species |
| Positive Controls | 293T | A431 | H1299 | HeLa | HepG2 | Raji |
| Target | FRAP1 |
| Predicted Target Size(KDa) | 288.95 |
| Cellular Localization | Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side | Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side | Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side |
| Form Supplied | Liquid |
| Concentration | 0.32 mg/ml |
| Purification | Purified by antigen-affinity chromatography. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |