| Catalog Number | GTX100133 |
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| Product Name | XPF antibody |
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| Full Name | excision repair cross-complementing rodent repair deficiency, complementation group 4 |
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| Synonyms | ERCC4|ERCC11|RAD1|XPF|excision repair cross-complementing rodent repair deficiency, complementation group 4 |
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| Product Description | Rabbit polyclonal antibody to XPF (excision repair cross-complementing rodent repair deficiency, complementation group 4) |
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| Background | The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6). |
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| Host | Rabbit |
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| Clonality | Polyclonal |
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| Immunogen | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 169 of Human XPF |
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| Antigen Species | Human |
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| Species Cross Reactivity | Human - Not yet tested in other species |
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| Predicted Cross Reactivity Species | mouse(93%) |
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| Application Note | Antibody reactive against recombinant protein, detects immunogen. Further validation in progress. |
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| Positive Controls | Target recombinant protein |
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| Target | XPF |
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| Predicted Target Size(KDa) | 105 |
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| Cellular Localization | Nucleus |
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| Form Supplied | Liquid |
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| Concentration | 6.01 mg/ml |
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| Purification | Affinity purified by Protein A. |
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| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
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| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
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| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
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