| Catalog Number | GTX100576 |
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| Product Name | ICAM5 antibody |
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| Full Name | intercellular adhesion molecule 5, telencephalin |
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| Synonyms | ICAM5|TLCN|TLN|intercellular adhesion molecule 5, telencephalin |
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| Product Description | Rabbit polyclonal antibody to ICAM5 (intercellular adhesion molecule 5, telencephalin) |
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| Background | The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases. [provided by RefSeq] |
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| Host | Rabbit |
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| Clonality | Polyclonal |
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| Immunogen | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 453 and 801 of Human ICAM5 |
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| Antigen Species | Human |
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| Species Cross Reactivity | Human - Not yet tested in other species |
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| Predicted Cross Reactivity Species | mouse(81%), rat(82%), rabbit(82%), cow(85%) |
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| Application Note | Antibody reactive against recombinant protein, detects immunogen. Further validation in progress. |
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| Positive Controls | Target recombinant protein |
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| Target | ICAM5 |
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| Predicted Target Size(KDa) | 97 |
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| Cellular Localization | Membrane; Single-pass type I membrane protein |
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| Form Supplied | Liquid |
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| Concentration | 0.7 mg/ml |
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| Purification | Purified by antigen-affinity chromatography. |
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| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
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| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
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| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
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