| Catalog Number | GTX101197 |
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| Product Name | Galactosylceramidase antibody |
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| Full Name | galactosylceramidase |
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| Synonyms | GALC|-|galactosylceramidase |
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| Product Description | Rabbit polyclonal antibody to Galactosylceramidase (galactosylceramidase) |
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| Background | This gene encodes a lysosomal protein which hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Mutations in this gene have been associated with Krabbe disease, also known as globoid cell leukodystrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq] |
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| Host | Rabbit |
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| Clonality | Polyclonal |
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| Immunogen | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 341 and 561 of Galactosylceramidase |
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| Antigen Species | Human |
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| Species Cross Reactivity | Human - Not yet tested in other species |
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| Predicted Cross Reactivity Species | dogs(87%), monkey(95%) |
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| Tested Applications | Western blot. The usefulness of this product in other applications has not been determined. |
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| Application Note | Suggested starting dilutions are as follows. WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. |
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| Positive Controls | A431 | H1299 | HeLa |
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| Target | Galactosylceramidase |
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| Predicted Target Size(KDa) | 77 |
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| Post-translation modification | Glycoprotein |
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| Cellular Localization | Lysosome |
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| Form Supplied | Liquid |
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| Concentration | 0.42 mg/ml |
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| Purification | Purified by antigen-affinity chromatography. |
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| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
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| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
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| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
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