| Catalog Number | GTX101291 |
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| Product Name | BCL2 antibody |
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| Full Name | B-cell CLL/lymphoma 2 |
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| Synonyms | BCL2|Bcl-2|B-cell CLL/lymphoma 2 |
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| Product Description | Rabbit polyclonal antibody to BCL2 (B-cell CLL/lymphoma 2) |
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| Background | This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. [provided by RefSeq] |
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| Host | Rabbit |
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| Clonality | Polyclonal |
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| Immunogen | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 62 and 215 of BCL2 |
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| Antigen Species | Human |
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| Species Cross Reactivity | human - Not yet tested in other species |
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| Predicted Cross Reactivity Species | mouse(100%), rat(99%), cow(99%), cat(98%), dogs(98%) |
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| Tested Applications | Western blot. The usefulness of this product in other applications has not been determined. |
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| Application Note | Suggested starting dilutions are as follows. WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. |
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| Positive Controls | NT2D | HeLa |
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| Target | BCL2 |
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| Predicted Target Size(KDa) | 26 |
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| Post-translation modification | Phosphoprotein |
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| Cellular Localization | Mitochondrion outer membrane | Nucleus membrane | Endoplasmic reticulum membrane |
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| Form Supplied | Liquid |
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| Concentration | 0.14 mg/ml |
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| Purification | Purified by antigen-affinity chromatography. |
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| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
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| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
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| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
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