| Catalog Number | GTX101515 |
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| Product Name | PABP antibody |
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| Full Name | poly(A) binding protein, cytoplasmic 1 |
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| Synonyms | PABPC1|PAB1|PABP|PABP1|PABPC2|PABPL1|poly(A) binding protein, cytoplasmic 1 |
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| Product Description | Rabbit polyclonal antibody to PABP (poly(A) binding protein, cytoplasmic 1) |
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| Background | The poly(A)-binding protein (PABP), which is found complexed to the 3-prime poly(A) tail of eukaryotic mRNA, is required for poly(A) shortening and translation initiation. In humans, the PABPs comprise a small nuclear isoform and a conserved gene family that displays at least 3 functional proteins: PABP1 (PABPC1), inducible PABP (iPABP, or PABPC4; MIM 603407), and PABP3 (PABPC3; MIM 604680). In addition, there are at least 4 pseudogenes, PABPCP1 to PABPCP4.[supplied by OMIM] |
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| Host | Rabbit |
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| Clonality | Polyclonal |
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| Immunogen | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 149 of PABP |
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| Antigen Species | Human |
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| Species Cross Reactivity | human - Not yet tested in other species |
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| Predicted Cross Reactivity Species | mouse(100%), rat(100%), cow(100%), zebra fish(97%) |
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| Tested Applications | Western blot. The usefulness of this product in other applications has not been determined. |
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| Application Note | Suggested starting dilutions are as follows. WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. |
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| Positive Controls | HepG2 |
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| Target | PABP |
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| Predicted Target Size(KDa) | 71 |
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| Post-translation modification | Phosphoprotein | Methylation | |
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| Cellular Localization | Cytoplasm | Nucleus |
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| Form Supplied | Liquid |
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| Concentration | 5.95 mg/ml |
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| Purification | Affinity purified by Protein A. |
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| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
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| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
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| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
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