| Catalog Number | GTX101785 |
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| Product Name | Mannose 6 Phosphate Receptor antibody |
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| Full Name | mannose-6-phosphate receptor (cation dependent) |
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| Synonyms | M6PR|CD-MPR|FLJ32994|MPR46|SMPR|mannose-6-phosphate receptor (cation dependent) |
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| Product Description | Rabbit polyclonal antibody to Mannose 6 Phosphate Receptor (mannose-6-phosphate receptor (cation dependent)) |
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| Background | The protein encoded by this gene is a receptor for mannose-6-phosphate groups on lysosomal enzymes. The receptor forms a homodimer or homotetramer for intracellular targeting of lysosomal enzymes and export of newly synthesized lysosomal enzymes into the cell secretions. The receptor is an integral membrane protein which localizes to the trans-Golgi reticulum, endosomes, and the plasma membrane. [provided by RefSeq] |
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| Host | Rabbit |
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| Clonality | Polyclonal |
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| Immunogen | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 180 of Human Mannose 6 Phosphate Receptor |
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| Antigen Species | Human |
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| Species Cross Reactivity | Human - Not yet tested in other species |
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| Predicted Cross Reactivity Species | mouse(93%), rat(93%), cow(91%) |
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| Application Note | Antibody reactive against recombinant protein, detects immunogen. Further validation in progress. |
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| Positive Controls | Target recombinant protein |
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| Target | Mannose 6 Phosphate Receptor |
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| Predicted Target Size(KDa) | 31 |
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| Cellular Localization | Lysosome membrane; Single-pass type I membrane protein |
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| Form Supplied | Liquid |
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| Concentration | 0.26 mg/ml |
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| Purification | Purified by antigen-affinity chromatography. |
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| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
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| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
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| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
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