| Catalog Number | GTX102267 |
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| Product Name | PBR antibody |
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| Full Name | translocator protein (18kDa) |
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| Synonyms | TSPO|BPBS|BZRP|DBI|IBP|MBR|PBR|PBS|PKBS|PTBR|mDRC|pk18|translocator protein (18kDa) |
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| Product Description | Rabbit polyclonal antibody to PBR (translocator protein (18kDa)) |
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| Background | Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq] |
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| Host | Rabbit |
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| Clonality | Polyclonal |
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| Immunogen | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 18 and 157 of Human PBR |
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| Antigen Species | Human |
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| Species Cross Reactivity | Human - Not yet tested in other species |
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| Predicted Cross Reactivity Species | mouse(86%), rat(86%), pig(87%) |
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| Application Note | Antibody reactive against recombinant protein, detects immunogen. Further validation in progress. |
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| Positive Controls | Target recombinant protein |
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| Target | PBR |
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| Predicted Target Size(KDa) | 19 |
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| Cellular Localization | Mitochondrion membrane; Multi-pass membrane protein |
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| Form Supplied | Liquid |
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| Concentration | 2 mg/ml |
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| Purification | Affinity purified by Protein A. |
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| Storage Buffer | 1XPBS, 40% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
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| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
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| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
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