| Catalog Number | GTX104676 |
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| Product Name | UBC3B antibody |
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| Full Name | ubiquitin-conjugating enzyme E2R 2 |
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| Synonyms | UBE2R2|CDC34B|FLJ20419|MGC10481|UBC3B|ubiquitin-conjugating enzyme E2R 2 |
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| Product Description | Rabbit polyclonal antibody to UBC3B (ubiquitin-conjugating enzyme E2R 2) |
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| Background | Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation. [provided by RefSeq] |
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| Host | Rabbit |
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| Clonality | Polyclonal |
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| Immunogen | Synthetic peptide contain a sequence corresponding to a region within amino acids 1 and 14 of Human UBC3B |
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| Antigen Species | Human |
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| Species Cross Reactivity | Human - Not yet tested in other species |
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| Application Note | Antibody reactive against peptide, detects immunogen. Further validation in progress. |
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| Positive Controls | Synthetic peptide: 1:8,000 |
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| Target | UBC3B |
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| Predicted Target Size(KDa) | 27 |
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| Form Supplied | Liquid |
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| Concentration | 8.65 mg/ml |
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| Purification | Affinity purified by Protein A. |
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| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
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| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
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| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
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