| Catalog Number | GTX105176 |
|---|
| Product Name | Ficolin-1 antibody |
|---|
| Full Name | ficolin (collagen/fibrinogen domain containing) 1 |
|---|
| Synonyms | FCN1|FCNM|ficolin (collagen/fibrinogen domain containing) 1 |
|---|
| Product Description | Rabbit polyclonal antibody to Ficolin-1 (ficolin (collagen/fibrinogen domain containing) 1) |
|---|
| Background | The ficolin family of proteins are characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. The collagen-like and the fibrinogen-like domains are also found separately in other proteins such as complement protein C1q, C-type lectins known as collectins, and tenascins. However, all these proteins recognize different targets, and are functionally distinct. Ficolin 1 encoded by FCN1 is predominantly expressed in the peripheral blood leukocytes, and has been postulated to function as a plasma protein with elastin-binding activity. [provided by RefSeq] |
|---|
| Host | Rabbit |
|---|
| Clonality | Polyclonal |
|---|
| Immunogen | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 18 and 294 of Human Ficolin-1 |
|---|
| Antigen Species | Human |
|---|
| Species Cross Reactivity | Human - Not yet tested in other species |
|---|
| Predicted Cross Reactivity Species | pig(81%) |
|---|
| Application Note | Antibody reactive against recombinant protein, detects immunogen. Further validation in progress. |
|---|
| Positive Controls | Target recombinant protein |
|---|
| Target | Ficolin-1 |
|---|
| Predicted Target Size(KDa) | 35 |
|---|
| Cellular Localization | Secreted |
|---|
| Form Supplied | Liquid |
|---|
| Concentration | 1 mg/ml |
|---|
| Purification | Purified by antigen-affinity chromatography. |
|---|
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
|---|
| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
|---|
| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
|---|