| Catalog Number | GTX105621 |
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| Product Name | TAF II p28 antibody |
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| Full Name | TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa |
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| Synonyms | TAF11|MGC:15243|PRO2134|TAF2I|TAFII28|TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa |
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| Product Description | Rabbit polyclonal antibody to TAF II p28 (TAF II p28 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa) |
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| Background | Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a small subunit of TFIID that is present in all TFIID complexes and interacts with TBP. This subunit also interacts with another small subunit, TAF13, to form a heterodimer with a structure similar to the histone core structure. [provided by RefSeq] |
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| Host | Rabbit |
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| Clonality | Polyclonal |
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| Immunogen | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 8 and 204 of Human TAF II p28 |
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| Antigen Species | Human |
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| Species Cross Reactivity | Human - Not yet tested in other species |
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| Predicted Cross Reactivity Species | mouse(93%), rat(94%), cow(95%), zebra fish(84%) |
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| Application Note | Antibody reactive against recombinant protein, detects immunogen. Further validation in progress. |
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| Positive Controls | Target recombinant protein |
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| Target | TAF II p28 |
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| Predicted Target Size(KDa) | 23 |
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| Cellular Localization | Nucleus |
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| Form Supplied | Liquid |
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| Concentration | 0.51 mg/ml |
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| Purification | Purified by antigen-affinity chromatography. |
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| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
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| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
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| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
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