| Catalog Number | GTX105686 |
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| Product Name | PAFAH1B3 antibody |
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| Full Name | platelet-activating factor acetylhydrolase, isoform Ib, gamma subunit 29kDa |
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| Synonyms | PAFAH1B3|FLJ44990|PAFAHG|platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) |
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| Product Description | Rabbit polyclonal antibody to PAFAH1B3 (platelet-activating factor acetylhydrolase, isoform Ib, gamma subunit 29kDa) |
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| Background | This gene encodes an acetylhydrolase that catalyzes the removal of an acetyl group from the glycerol backbone of platelet-activating factor. The encoded enzyme is a subunit of the platelet-activating factor acetylhydrolase isoform 1B complex, which consists of the catalytic beta and gamma subunits and the regulatory alpha subunit. This complex functions in brain development. A translocation between this gene on chromosome 19 and the CDC-like kinase 2 gene on chromosome 1 has been observed, and was associated with mental retardation, ataxia, and atrophy of the brain. Alternatively spliced transcript variants have been described. [provided by RefSeq] |
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| Host | Rabbit |
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| Clonality | Polyclonal |
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| Immunogen | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 197 of Human PAFAH1B3 |
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| Antigen Species | Human |
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| Species Cross Reactivity | Human - Not yet tested in other species |
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| Predicted Cross Reactivity Species | mouse(96%), rat(96%), cow(98%) |
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| Application Note | Antibody reactive against recombinant protein, detects immunogen. Further validation in progress. |
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| Positive Controls | Target recombinant protein |
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| Target | PAFAH1B3 |
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| Predicted Target Size(KDa) | 26 |
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| Cellular Localization | Cytoplasm |
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| Form Supplied | Liquid |
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| Concentration | 0.62 mg/ml |
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| Purification | Purified by antigen-affinity chromatography. |
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| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
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| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
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| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
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